Chargers
0-4 • L4
Colts
2-2 • W2
Chargers vs Colts Prediction Today — AI NFL Pick
Updated October 9, 2026 at 1:13 PM EDT · refreshed throughout the day
Team Form & Stats
Away
Chargers
Season Record
Home
Colts
Season Record
Chargers vs Colts Prediction
Our AI model analyzes 18 factors to generate Chargers vs Colts predictions, including ELO ratings, recent form, injuries, rest days, and market odds from 7+ sportsbooks. Predictions for this matchup will appear once the game is scheduled and odds become available.
When available, you'll see AI moneyline picks — each with a confidence score, edge vs. market odds, and AI-generated analysis explaining the reasoning behind every pick. NFL matchup predictions publish the Tuesday before game day once the week's schedule and opening lines are set.
Chargers vs Colts Matchup Outlook
Heading into this NFL matchup, the Chargers carry a 0-4 record on a L4 run, while the Colts sit at 2-2 (W2). Over their last 10 games, the Chargers are 0-4 and the Colts are 2-2.
Situationally, the Colts are 1-1 at home this season and the Chargers are 0-2 on the road — a split our model weights heavily when generating NFL moneyline picks.
How do NFL predictions work?
Da Vinci Bets uses machine learning models trained on thousands of historical NFL games. Each prediction considers team strength (ELO ratings), recent performance trends, head-to-head history, home/away splits, rest advantages, injury impact, and real-time odds movement across major sportsbooks.
Predictions refresh every 4 hours with odds updating every 3-10 minutes during active windows. All results are settled against final scores.
More NFL Predictions
Every NFL Pick.
Every Edge
Our AI model analyzes 18 factors per NFL game — SRS, Pythagorean expectation, injuries, weather, and sharp movement.
3-day free trial • Cancel anytime