AI Picks for Wednesday, April 22, 2026

Pick: Padres·1% conf·Score: 1-0

Padres @ Rockies

Pick: Angels·1% conf·Score: 4-2

Blue Jays @ Angels

Pick: Diamondbacks·1% conf·Score: 11-5

White Sox @ Diamondbacks

Pick: Mariners·1% conf·Score: 5-2

Athletics @ Mariners

Pick: Dodgers·1% conf·Score: 1-3

Dodgers @ Giants

Pick: Marlins·1% conf·Score: 1-4

Cardinals @ Marlins

Pick: Guardians·1% conf·Score: 2-0

Astros @ Guardians

Pick: Rays·1% conf·Score: 1-6

Reds @ Rays

Pick: Royals·1% conf·Score: 8-6

Orioles @ Royals

Pick: Angels·1% conf·Score: 3-7

Blue Jays @ Angels

Pick: Mariners·1% conf·Score: 4-5

Athletics @ Mariners

Pick: Tigers·1% conf·Score: 2-5

Brewers @ Tigers

Pick: Yankees·1% conf·Score: 4-1

Yankees @ Red Sox

Pick: Braves·1% conf·Score: 8-6

Braves @ Nationals

Pick: Mets·1% conf·Score: 2-3

Twins @ Mets

Pick: Cubs·1% conf·Score: 2-7

Phillies @ Cubs

Pick: Spurs·1% conf·Score: 106-103

NBA

1/3 correct

Portland Trail Blazers @ San Antonio Spurs

Pick: Lakers·1% conf·Score: 94-101

Houston Rockets @ Los Angeles Lakers

Pick: Magic·1% conf·Score: 83-98

Orlando Magic @ Detroit Pistons

Pick: Utah Mammoth·1% conf·Score: 3-2

NHL

2/3 correct

Utah Mammoth @ Vegas Golden Knights

Pick: Colorado Avalanche·1% conf·Score: 1-2

Los Angeles Kings @ Colorado Avalanche

Pick: Pittsburgh Penguins·1% conf·Score: 2-5

Pittsburgh Penguins @ Philadelphia Flyers

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